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Over the past year, you may have seen something called delta-8 THC or
"delta 8" appear in convenience stores and pharmacies alongside CBD
gummies, oils and lotions.Delta-8 THC is a hemp-derived compound that's closely
related to delta-9 THC - what's commonly called THC and is the psychoactive
component of cannabis that's responsible for the high that users feel.
Like garden variety marijuana, delta-8 THC can be vaped
or eaten. However, it's rarely smoked. Anecdotally, its fans swear by its benefits
- that it helps with relaxation and pain relief without intense highs that can
veer into anxiety or paranoia. Yet
there's been a dearth of research on this compound. As public health scholars,
we decided to conduct the first survey of delta-8 THC users to find out who was
using it, why they were using it and what sort of effects it had.
The latest
cannabinoid to storm the market
The 2018 Agriculture Improvement Act - also known as the
farm bill - legalized the sale of hemp-derived compounds. The widely available
CBD is a hemp-derived compound.Delta-8 THC is another. It's an isomer, or
chemical analog, of THC. The difference is in the position of a double bond in
the carbon ring, which makes delta-8 THC have a lower affinity for the CB1
receptor of the endocannabinoid system in our brains. For this reason, it may
be less potent than THC and cause a less-intense high.
Delta-8 tetrahydrocannabinol (delta-8 THC) is a
cannabinoid from Cannabis sativa. It's similar to delta-9 THC, the main
psychoactive compound in cannabis.
Cannabinoids in cannabis work by binding to sites in the
brain and on the nerves. Delta-8 THC is similar to delta-9 THC, but appears to
be less psychoactive. The natural concentration of delta-8 THC in cannabis and
hemp is low, so most delta-8 THC is synthetically made in a lab.
People use delta-8 THC for nausea and vomiting caused by
cancer drug treatment, glaucoma, trouble sleeping, and many other conditions,
but there is no good scientific evidence to support these uses.
Keep in mind that delta-8 THC hasn't been evaluated by
the US FDA for safety, and legality isn't clear. It's banned in some states,
and legal in others. Also, the amount of delta-8 THC in products might vary significantly. Some products might
also contain contaminants.
When taken by mouth: There isn't enough reliable
information to know if delta-8 THC is safe. It might cause side effects such as
difficulty thinking and speaking, and feeling "high." Regular use
might also cause cannabinoid hyperemesis syndrome (CHS). CHS leads to severe
nausea and vomiting that doesn't respond to typical anti-nausea drugs.
What Effect
Does -8 THC Have On The Body?
Synthetic Delta-8, derived from hemp-based CBD, is used
by people to treat numerous ailments, including inflammation, insomnia,
digestion problems, stress, depression and pain. It is a chemical compound that
is also advantageous for people having degenerative neural disorders. Because
Delta-8 interferes with the activity of neurotransmitters, it is effective for
people with brain-related disorders. It generates the activity of neurons that
help the brain with memory and understanding.
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